A multi-functional PEGylated gold(iii) compound: potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery

Furan-functionalized co-polymers for targeted drug delivery: characterization, self-assembly and drug encapsulation.

We have previously reported furan-maleimide Diels-Alder chemistry as a new methodology to couple maleimide-modified antibodies on furan-functionalized polymeric carriers in the preparation of immuno-nanoparticles for targeted drug delivery. In this report, we focus on the characterization, self-assembly behavior and drug encapsulation of two types of furan-functionalized co-polymers: poly(2-met...

Co -delivery of Sulforaphane and Curcumin with PEGylated Iron Oxide-Gold Core Shell Nanoparticles for delivery to breast cancer cell line

Co-delivery approach has been recommended to reduce the amount of each drug and to achieve the synergistic effect for cancer treatment. CUR and SF have antitumor effects, but their application is limited because of their low water solubility and poor oral bioavailability. To improve the bioavailability and solubility of SF and CUR, we performed an innovative co-delivery of SF and CUR with magne...

Co -delivery of Sulforaphane and Curcumin with PEGylated Iron Oxide-Gold Core Shell Nanoparticles for delivery to breast cancer cell line

Co-delivery approach has been recommended to reduce the amount of each drug and to achieve the synergistic effect for cancer treatment. CUR and SF have antitumor effects, but their application is limited because of their low water solubility and poor oral bioavailability. To improve the bioavailability and solubility of SF and CUR, we performed an innovative co-delivery of SF and CUR with magne...

Self Assembly Systems for Surface Modification and Drug Delivery

Self-assembled monolayers (SAMs) are ordered molecular assemblies that form spontaneously by the adsorption of a surfactant with a specific affinity of its headgroup to a substrate. The present work aims at developing a new monomolecular PEG-based adlayer system and its protein resistance properties, by exploiting the spontaneous formation of alkane phosphate SAMs on titanium oxide and their ca...

Ubiocompatible and Biomimetic Self-assembly of Functional Nanostructures